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Biomarker-Guided Adaptive Trial Designs in Phase II and Phase III: A Methodological Review
BACKGROUND: Personalized medicine is a growing area of research which aims to tailor the treatment given to a patient according to one or more personal characteristics. These characteristics can be demographic such as age or gender, or biological such as a genetic or other biomarker. Prior to utiliz...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766245/ https://www.ncbi.nlm.nih.gov/pubmed/26910238 http://dx.doi.org/10.1371/journal.pone.0149803 |