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De Novo Genome Assembly Shows Genome Wide Similarity between Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense

BACKGROUND: Trypanosoma brucei is a eukaryotic pathogen which causes African trypanosomiasis. It is notable for its variant surface glycoprotein (VSG) coat, which undergoes antigenic variation enabled by a large suite of VSG pseudogenes, allowing for persistent evasion of host adaptive immunity. Whi...

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Detalles Bibliográficos
Autores principales: Sistrom, Mark, Evans, Benjamin, Benoit, Joshua, Balmer, Oliver, Aksoy, Serap, Caccone, Adalgisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766357/
https://www.ncbi.nlm.nih.gov/pubmed/26910229
http://dx.doi.org/10.1371/journal.pone.0147660