Visualization and quantification of deformation behavior of clopidogrel bisulfate polymorphs during tableting

The deformation behavior of particles under pressure dominates the mechanical properties of solid dosage forms. In this study, the in situ 3D deformation of two polymorphs (I and II) of clopidogrel bisulfate (CLP) was determined to illustrate pressure distribution profiles within the tablet by the d...

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Detalles Bibliográficos
Autores principales: Yin, Xian-Zhen, Wu, Li, Li, Ying, Guo, Tao, Li, Hai-Yan, Xiao, Ti-Qiao, York, Peter, Nangia, Ashwini, Gui, Shuang-Ying, Zhang, Ji-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766417/
https://www.ncbi.nlm.nih.gov/pubmed/26911359
http://dx.doi.org/10.1038/srep21770

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766417/
https://www.ncbi.nlm.nih.gov/pubmed/26911359
http://dx.doi.org/10.1038/srep21770

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