Essential Roles of RNA-binding Protein HuR in Activation of Hepatic Stellate Cells Induced by Transforming Growth Factor-β1

RNA-binding protein HuR mediates transforming growth factor (TGF)-β1-induced profibrogenic actions. Up-regulation of Sphingosine kinase 1 (SphK1) is involved in TGF-β1-induced activation of hepatic stellate cells (HSCs) in liver fibrogenesis. However, the molecular mechanism of TGF-β1 regulates SphK...

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Detalles Bibliográficos
Autores principales: Ge, Jingjing, Chang, Na, Zhao, Zhongxin, Tian, Lei, Duan, Xianghui, Yang, Lin, Li, Liying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766441/
https://www.ncbi.nlm.nih.gov/pubmed/26912347
http://dx.doi.org/10.1038/srep22141

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