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A novel peptide with potent and broad-spectrum antiviral activities against multiple respiratory viruses

A safe, potent and broad-spectrum antiviral is urgently needed to combat emerging respiratory viruses. In light of the broad antiviral activity of β-defensins, we tested the antiviral activity of 11 peptides derived from mouse β-defensin-4 and found that a short peptide, P9, exhibited potent and bro...

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Detalles Bibliográficos
Autores principales: Zhao, Hanjun, Zhou, Jie, Zhang, Ke, Chu, Hin, Liu, Dabin, Poon, Vincent Kwok-Man, Chan, Chris Chung-Sing, Leung, Ho-Chuen, Fai, Ng, Lin, Yong-Ping, Zhang, Anna Jin-Xia, Jin, Dong-Yan, Yuen, Kwok-Yung, Zheng, Bo-Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766503/
https://www.ncbi.nlm.nih.gov/pubmed/26911565
http://dx.doi.org/10.1038/srep22008