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Susceptibility to N-methyl-N-nitrosourea-induced retinal degeneration in different rat strains
To evaluate the potential role of genetic background in the susceptibility to retinal degeneration induced by N-methyl-N-nitrosourea (MNU), female rats of the Sprague-Dawley (SD), Long-Evans (LE) and Copenhagen (CH) strains were administered 50 mg/kg MNU or saline at 7 weeks of age. Retina morpholog...
Autores principales: | Emoto, Yuko, Yoshizawa, Katsuhiko, Kinoshita, Yuichi, Yuki, Michiko, Yuri, Takashi, Tsubura, Airo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Japanese Society of Toxicologic Pathology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766522/ https://www.ncbi.nlm.nih.gov/pubmed/26989305 http://dx.doi.org/10.1293/tox.2015-0062 |
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