Identifying protective Streptococcus pyogenes vaccine antigens recognized by both B and T cells in human adults and children

No commercial vaccine exists against Group A streptococci (GAS; Streptococcus pyogenes) and only little is known about anti-GAS protective immunity. In our effort to discover new protective vaccine candidates, we selected 21 antigens based on an in silico evaluation. These were all well-conserved am...

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Detalles Bibliográficos
Autores principales: Mortensen, Rasmus, Nissen, Thomas Nørrelykke, Fredslund, Sine, Rosenkrands, Ida, Christensen, Jan Pravsgaard, Andersen, Peter, Dietrich, Jes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766568/
https://www.ncbi.nlm.nih.gov/pubmed/26911649
http://dx.doi.org/10.1038/srep22030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766568/
https://www.ncbi.nlm.nih.gov/pubmed/26911649
http://dx.doi.org/10.1038/srep22030

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