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Inhibition of the STAT3 signaling pathway contributes to apigenin-mediated anti-metastatic effect in melanoma

Signal transducer and activator of transcription 3 (STAT3) signaling is constantly activated in human melanoma, and promotes melanoma metastasis. The dietary flavonoid apigenin is a bioactive compound that possesses low toxicity and exerts anti-metastatic activity in melanoma. However, the anti-meta...

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Detalles Bibliográficos
Autores principales: Cao, Hui-Hui, Chu, Jian-Hong, Kwan, Hiu-Yee, Su, Tao, Yu, Hua, Cheng, Chi-Yan, Fu, Xiu-Qiong, Guo, Hui, Li, Ting, Tse, Anfernee Kai-Wing, Chou, Gui-Xin, Mo, Huan-Biao, Yu, Zhi-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766576/
https://www.ncbi.nlm.nih.gov/pubmed/26911838
http://dx.doi.org/10.1038/srep21731