The role of lipid droplet formation in the protection of unsaturated fatty acids against palmitic acid induced lipotoxicity to rat insulin-producing cells

BACKGROUND: Type 2 diabetes is associated with increased plasma concentrations of non-esterified fatty acids (NEFAs), which trigger pancreatic β-cell dysfunction and apoptosis. Only long-chain saturated NEFAs induced lipotoxicity in rat insulin-producing cells in in vitro experiments, whereas unsatu...

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Detalles Bibliográficos
Autores principales: Plötz, Thomas, Hartmann, Magnus, Lenzen, Sigurd, Elsner, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766664/
https://www.ncbi.nlm.nih.gov/pubmed/26918025
http://dx.doi.org/10.1186/s12986-016-0076-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766664/
https://www.ncbi.nlm.nih.gov/pubmed/26918025
http://dx.doi.org/10.1186/s12986-016-0076-z

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