Lower IgG somatic hypermutation rates during acute dengue virus infection is compatible with a germinal center-independent B cell response

BACKGROUND: The study of human B cell response to dengue virus (DENV) infection is critical to understand serotype-specific protection and the cross-reactive sub-neutralizing response. Whereas the first is beneficial and thus represents the ultimate goal of vaccination, the latter has been implicate...

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Detalles Bibliográficos
Autores principales: Godoy-Lozano, Elizabeth Ernestina, Téllez-Sosa, Juan, Sánchez-González, Gilberto, Sámano-Sánchez, Hugo, Aguilar-Salgado, Andrés, Salinas-Rodríguez, Aarón, Cortina-Ceballos, Bernardo, Vivanco-Cid, Héctor, Hernández-Flores, Karina, Pfaff, Jennifer M., Kahle, Kristen M., Doranz, Benjamin J., Gómez-Barreto, Rosa Elena, Valdovinos-Torres, Humberto, López-Martínez, Irma, Rodriguez, Mario H., Martínez-Barnetche, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766701/
https://www.ncbi.nlm.nih.gov/pubmed/26917418
http://dx.doi.org/10.1186/s13073-016-0276-1

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