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Trimming of sequence reads alters RNA-Seq gene expression estimates
BACKGROUND: High-throughput RNA-Sequencing (RNA-Seq) has become the preferred technique for studying gene expression differences between biological samples and for discovering novel isoforms, though the techniques to analyze the resulting data are still immature. One pre-processing step that is wide...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766705/ https://www.ncbi.nlm.nih.gov/pubmed/26911985 http://dx.doi.org/10.1186/s12859-016-0956-2 |