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Alterations in Mitochondrial and Endoplasmic Reticulum Signaling by p53 Mutants
The p53 protein is probably the most important tumor suppressor, acting as a nuclear transcription factor primarily through the modulation of cell death. However, currently, it is well accepted that p53 can also exert important transcription-independent pro-cell death actions. Indeed, cytosolic loca...
Autores principales: | Giorgi, Carlotta, Bonora, Massimo, Missiroli, Sonia, Morganti, Claudia, Morciano, Giampaolo, Wieckowski, Mariusz R., Pinton, Paolo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766755/ https://www.ncbi.nlm.nih.gov/pubmed/26942128 http://dx.doi.org/10.3389/fonc.2016.00042 |
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