Current status of pyrazole and its biological activities

Pyrazole are potent medicinal scaffolds and exhibit a full spectrum of biological activities. This review throws light on the detailed synthetic approaches which have been applied for the synthesis of pyrazole. This has been followed by an in depth analysis of the pyrazole with respect to their medi...

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Autores principales: Naim, Mohd Javed, Alam, Ozair, Nawaz, Farah, Alam, Md. Jahangir, Alam, Perwaiz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766773/
https://www.ncbi.nlm.nih.gov/pubmed/26957862
http://dx.doi.org/10.4103/0975-7406.171694
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author Naim, Mohd Javed
Alam, Ozair
Nawaz, Farah
Alam, Md. Jahangir
Alam, Perwaiz
author_facet Naim, Mohd Javed
Alam, Ozair
Nawaz, Farah
Alam, Md. Jahangir
Alam, Perwaiz
author_sort Naim, Mohd Javed
collection PubMed
description Pyrazole are potent medicinal scaffolds and exhibit a full spectrum of biological activities. This review throws light on the detailed synthetic approaches which have been applied for the synthesis of pyrazole. This has been followed by an in depth analysis of the pyrazole with respect to their medical significance. This follow-up may help the medicinal chemists to generate new leads possessing pyrazole nucleus with high efficacy.
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spelling pubmed-47667732016-03-08 Current status of pyrazole and its biological activities Naim, Mohd Javed Alam, Ozair Nawaz, Farah Alam, Md. Jahangir Alam, Perwaiz J Pharm Bioallied Sci Review Article Pyrazole are potent medicinal scaffolds and exhibit a full spectrum of biological activities. This review throws light on the detailed synthetic approaches which have been applied for the synthesis of pyrazole. This has been followed by an in depth analysis of the pyrazole with respect to their medical significance. This follow-up may help the medicinal chemists to generate new leads possessing pyrazole nucleus with high efficacy. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC4766773/ /pubmed/26957862 http://dx.doi.org/10.4103/0975-7406.171694 Text en Copyright: © Journal of Pharmacy and Bioallied Sciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Review Article
Naim, Mohd Javed
Alam, Ozair
Nawaz, Farah
Alam, Md. Jahangir
Alam, Perwaiz
Current status of pyrazole and its biological activities
title Current status of pyrazole and its biological activities
title_full Current status of pyrazole and its biological activities
title_fullStr Current status of pyrazole and its biological activities
title_full_unstemmed Current status of pyrazole and its biological activities
title_short Current status of pyrazole and its biological activities
title_sort current status of pyrazole and its biological activities
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766773/
https://www.ncbi.nlm.nih.gov/pubmed/26957862
http://dx.doi.org/10.4103/0975-7406.171694
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