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Hedonic sensitivity to low-dose ketamine is modulated by gonadal hormones in a sex-dependent manner

We recently reported a greater sensitivity of female rats to rapid antidepressant-like effects of ketamine compared to male rats, and that ovarian-derived estradiol (E2) and progesterone (P4) are essential for this response. However, to what extent testosterone may also contribute, and whether durat...

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Detalles Bibliográficos
Autores principales:	Saland, Samantha K., Schoepfer, Kristin J., Kabbaj, Mohamed
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766854/ https://www.ncbi.nlm.nih.gov/pubmed/26888470 http://dx.doi.org/10.1038/srep21322

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