Factors Associated with Loss to Follow-up during Treatment for Multidrug-Resistant Tuberculosis, the Philippines, 2012–2014

To identify factors associated with loss to follow-up during treatment for multidrug-resistant (MDR) tuberculosis (TB) in the Philippines, we conducted a case–control study of adult patients who began receiving treatment for rifampin-resistant TB during July 1–December 31, 2012. Among 91 case-patien...

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Autores principales: Tupasi, Thelma E., Garfin, Anna Marie Celina G., Kurbatova, Ekaterina V., Mangan, Joan M., Orillaza-Chi, Ruth, Naval, Leilani C., Balane, Glenn I., Basilio, Ramon, Golubkov, Alexander, Joson, Evelyn S., Lew, Woo-jin, Lofranco, Vivian, Mantala, Mariquita, Pancho, Stuart, Sarol, Jesus N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766881/
https://www.ncbi.nlm.nih.gov/pubmed/26889786
http://dx.doi.org/10.3201/eid2203.151788
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author Tupasi, Thelma E.
Garfin, Anna Marie Celina G.
Kurbatova, Ekaterina V.
Mangan, Joan M.
Orillaza-Chi, Ruth
Naval, Leilani C.
Balane, Glenn I.
Basilio, Ramon
Golubkov, Alexander
Joson, Evelyn S.
Lew, Woo-jin
Lofranco, Vivian
Mantala, Mariquita
Pancho, Stuart
Sarol, Jesus N.
author_facet Tupasi, Thelma E.
Garfin, Anna Marie Celina G.
Kurbatova, Ekaterina V.
Mangan, Joan M.
Orillaza-Chi, Ruth
Naval, Leilani C.
Balane, Glenn I.
Basilio, Ramon
Golubkov, Alexander
Joson, Evelyn S.
Lew, Woo-jin
Lofranco, Vivian
Mantala, Mariquita
Pancho, Stuart
Sarol, Jesus N.
author_sort Tupasi, Thelma E.
collection PubMed
description To identify factors associated with loss to follow-up during treatment for multidrug-resistant (MDR) tuberculosis (TB) in the Philippines, we conducted a case–control study of adult patients who began receiving treatment for rifampin-resistant TB during July 1–December 31, 2012. Among 91 case-patients (those lost to follow-up) and 182 control-patients (those who adhered to treatment), independent factors associated with loss to follow-up included patients’ higher self-rating of the severity of vomiting as an adverse drug reaction and alcohol abuse. Protective factors included receiving any type of assistance from the TB program, better TB knowledge, and higher levels of trust in and support from physicians and nurses. These results provide insights for designing interventions aimed at reducing patient loss to follow-up during treatment for MDR TB.
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spelling pubmed-47668812016-03-01 Factors Associated with Loss to Follow-up during Treatment for Multidrug-Resistant Tuberculosis, the Philippines, 2012–2014 Tupasi, Thelma E. Garfin, Anna Marie Celina G. Kurbatova, Ekaterina V. Mangan, Joan M. Orillaza-Chi, Ruth Naval, Leilani C. Balane, Glenn I. Basilio, Ramon Golubkov, Alexander Joson, Evelyn S. Lew, Woo-jin Lofranco, Vivian Mantala, Mariquita Pancho, Stuart Sarol, Jesus N. Emerg Infect Dis Research To identify factors associated with loss to follow-up during treatment for multidrug-resistant (MDR) tuberculosis (TB) in the Philippines, we conducted a case–control study of adult patients who began receiving treatment for rifampin-resistant TB during July 1–December 31, 2012. Among 91 case-patients (those lost to follow-up) and 182 control-patients (those who adhered to treatment), independent factors associated with loss to follow-up included patients’ higher self-rating of the severity of vomiting as an adverse drug reaction and alcohol abuse. Protective factors included receiving any type of assistance from the TB program, better TB knowledge, and higher levels of trust in and support from physicians and nurses. These results provide insights for designing interventions aimed at reducing patient loss to follow-up during treatment for MDR TB. Centers for Disease Control and Prevention 2016-03 /pmc/articles/PMC4766881/ /pubmed/26889786 http://dx.doi.org/10.3201/eid2203.151788 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research
Tupasi, Thelma E.
Garfin, Anna Marie Celina G.
Kurbatova, Ekaterina V.
Mangan, Joan M.
Orillaza-Chi, Ruth
Naval, Leilani C.
Balane, Glenn I.
Basilio, Ramon
Golubkov, Alexander
Joson, Evelyn S.
Lew, Woo-jin
Lofranco, Vivian
Mantala, Mariquita
Pancho, Stuart
Sarol, Jesus N.
Factors Associated with Loss to Follow-up during Treatment for Multidrug-Resistant Tuberculosis, the Philippines, 2012–2014
title Factors Associated with Loss to Follow-up during Treatment for Multidrug-Resistant Tuberculosis, the Philippines, 2012–2014
title_full Factors Associated with Loss to Follow-up during Treatment for Multidrug-Resistant Tuberculosis, the Philippines, 2012–2014
title_fullStr Factors Associated with Loss to Follow-up during Treatment for Multidrug-Resistant Tuberculosis, the Philippines, 2012–2014
title_full_unstemmed Factors Associated with Loss to Follow-up during Treatment for Multidrug-Resistant Tuberculosis, the Philippines, 2012–2014
title_short Factors Associated with Loss to Follow-up during Treatment for Multidrug-Resistant Tuberculosis, the Philippines, 2012–2014
title_sort factors associated with loss to follow-up during treatment for multidrug-resistant tuberculosis, the philippines, 2012–2014
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766881/
https://www.ncbi.nlm.nih.gov/pubmed/26889786
http://dx.doi.org/10.3201/eid2203.151788
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