Preliminary Favorable Outcome for Medically and Surgically Managed Extensively Drug-Resistant Tuberculosis, France, 2009–2014

We report 20 cases of extensively drug-resistant tuberculosis managed in France. Treatment was individualized and included bedaquiline and linezolid for most patients and surgery in 8 patients. At last follow-up (22 months), 19 patients had achieved conversion from positive to negative on culture te...

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Autores principales: Henry, Benoît, Revest, Matthieu, Dournon, Nathalie, Epelboin, Loïc, Mellon, Guillaume, Bellaud, Guillaume, Mordant, Pierre, Le Dû, Damien, Véziris, Nicolas, Bernard, Christine, Morel, Sébastien, Jauréguiberry, Stéphane, Michelet, Christian, Bricaire, François, Tattevin, Pierre, Caumes, Éric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2016
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766883/
https://www.ncbi.nlm.nih.gov/pubmed/26891089
http://dx.doi.org/10.3201/eid2203.151130
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author Henry, Benoît
Revest, Matthieu
Dournon, Nathalie
Epelboin, Loïc
Mellon, Guillaume
Bellaud, Guillaume
Mordant, Pierre
Le Dû, Damien
Véziris, Nicolas
Bernard, Christine
Morel, Sébastien
Jauréguiberry, Stéphane
Michelet, Christian
Bricaire, François
Tattevin, Pierre
Caumes, Éric
author_facet Henry, Benoît
Revest, Matthieu
Dournon, Nathalie
Epelboin, Loïc
Mellon, Guillaume
Bellaud, Guillaume
Mordant, Pierre
Le Dû, Damien
Véziris, Nicolas
Bernard, Christine
Morel, Sébastien
Jauréguiberry, Stéphane
Michelet, Christian
Bricaire, François
Tattevin, Pierre
Caumes, Éric
author_sort Henry, Benoît
collection PubMed
description We report 20 cases of extensively drug-resistant tuberculosis managed in France. Treatment was individualized and included bedaquiline and linezolid for most patients and surgery in 8 patients. At last follow-up (22 months), 19 patients had achieved conversion from positive to negative on culture testing. These promising results of comprehensive management obtained in a small series deserve confirmation.
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spelling pubmed-47668832016-03-01 Preliminary Favorable Outcome for Medically and Surgically Managed Extensively Drug-Resistant Tuberculosis, France, 2009–2014 Henry, Benoît Revest, Matthieu Dournon, Nathalie Epelboin, Loïc Mellon, Guillaume Bellaud, Guillaume Mordant, Pierre Le Dû, Damien Véziris, Nicolas Bernard, Christine Morel, Sébastien Jauréguiberry, Stéphane Michelet, Christian Bricaire, François Tattevin, Pierre Caumes, Éric Emerg Infect Dis Dispatch We report 20 cases of extensively drug-resistant tuberculosis managed in France. Treatment was individualized and included bedaquiline and linezolid for most patients and surgery in 8 patients. At last follow-up (22 months), 19 patients had achieved conversion from positive to negative on culture testing. These promising results of comprehensive management obtained in a small series deserve confirmation. Centers for Disease Control and Prevention 2016-03 /pmc/articles/PMC4766883/ /pubmed/26891089 http://dx.doi.org/10.3201/eid2203.151130 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Henry, Benoît
Revest, Matthieu
Dournon, Nathalie
Epelboin, Loïc
Mellon, Guillaume
Bellaud, Guillaume
Mordant, Pierre
Le Dû, Damien
Véziris, Nicolas
Bernard, Christine
Morel, Sébastien
Jauréguiberry, Stéphane
Michelet, Christian
Bricaire, François
Tattevin, Pierre
Caumes, Éric
Preliminary Favorable Outcome for Medically and Surgically Managed Extensively Drug-Resistant Tuberculosis, France, 2009–2014
title Preliminary Favorable Outcome for Medically and Surgically Managed Extensively Drug-Resistant Tuberculosis, France, 2009–2014
title_full Preliminary Favorable Outcome for Medically and Surgically Managed Extensively Drug-Resistant Tuberculosis, France, 2009–2014
title_fullStr Preliminary Favorable Outcome for Medically and Surgically Managed Extensively Drug-Resistant Tuberculosis, France, 2009–2014
title_full_unstemmed Preliminary Favorable Outcome for Medically and Surgically Managed Extensively Drug-Resistant Tuberculosis, France, 2009–2014
title_short Preliminary Favorable Outcome for Medically and Surgically Managed Extensively Drug-Resistant Tuberculosis, France, 2009–2014
title_sort preliminary favorable outcome for medically and surgically managed extensively drug-resistant tuberculosis, france, 2009–2014
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766883/
https://www.ncbi.nlm.nih.gov/pubmed/26891089
http://dx.doi.org/10.3201/eid2203.151130
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