Lysine-functionalized nanodiamonds as gene carriers: development of stable colloidal dispersion for in vitro cellular uptake studies and siRNA delivery application

PURPOSE: Nanodiamonds (NDs) are emerging as an attractive tool for gene therapeutics. To reach their full potential for biological application, NDs should maintain their colloidal stability in biological milieu. This study describes the behavior of lysine-functionalized ND (lys-ND) in various disper...

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Detalles Bibliográficos
Autores principales: Alwani, Saniya, Kaur, Randeep, Michel, Deborah, Chitanda, Jackson M, Verrall, Ronald E, Karunakaran, Chithra, Badea, Ildiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767059/
https://www.ncbi.nlm.nih.gov/pubmed/26929623
http://dx.doi.org/10.2147/IJN.S92218

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