Cargando…

Molecular insights into the enzymatic diversity of flavin‐trafficking protein (Ftp; formerly ApbE) in flavoprotein biogenesis in the bacterial periplasm

We recently reported a flavin‐trafficking protein (Ftp) in the syphilis spirochete Treponema pallidum (Ftp_Tp) as the first bacterial metal‐dependent FAD pyrophosphatase that hydrolyzes FAD into AMP and FMN in the periplasm. Orthologs of Ftp_Tp in other bacteria (formerly ApbE) appear to lack this h...

Descripción completa

Detalles Bibliográficos
Autores principales:	Deka, Ranjit K., Brautigam, Chad A., Liu, Wei Z., Tomchick, Diana R., Norgard, Michael V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767422/ https://www.ncbi.nlm.nih.gov/pubmed/26626129 http://dx.doi.org/10.1002/mbo3.306

Ejemplares similares

Evidence for Posttranslational Protein Flavinylation in the Syphilis Spirochete Treponema pallidum: Structural and Biochemical Insights from the Catalytic Core of a Periplasmic Flavin-Trafficking Protein
por: Deka, Ranjit K., et al.
Publicado: (2015)

Remaining challenges in cellular flavin cofactor homeostasis and flavoprotein biogenesis
por: Giancaspero, Teresa A., et al.
Publicado: (2015)

Noncovalent interactions that tune the reactivities of the flavins in bifurcating electron transferring flavoprotein
por: González-Viegas, María, et al.
Publicado: (2023)

Unusual reactivity of a flavin in a bifurcating electron-transferring flavoprotein leads to flavin modification and a charge-transfer complex
por: Mohamed-Raseek, Nishya, et al.
Publicado: (2022)

The Tp0684 (MglB-2) Lipoprotein of Treponema pallidum: A Glucose-Binding Protein with Divergent Topology
por: Brautigam, Chad A., et al.
Publicado: (2016)

Biophysical and Biochemical Characterization of TP0037, a d-Lactate Dehydrogenase, Supports an Acetogenic Energy Conservation Pathway in Treponema pallidum
por: Deka, Ranjit K., et al.
Publicado: (2020)

The 2′-hydroxy group of flavin mononucleotide influences the catalytic function and promiscuity of the flavoprotein iodotyrosine dehalogenase
por: Kozyryev, Anton, et al.
Publicado: (2023)

Rapid kinetics reveal surprising flavin chemistry in bifurcating electron transfer flavoprotein from Acidaminococcus fermentans
por: Sucharitakul, Jeerus, et al.
Publicado: (2020)

Contrasting roles for two conserved arginines: Stabilizing flavin semiquinone or quaternary structure, in bifurcating electron transfer flavoproteins
por: Mohamed-Raseek, Nishya, et al.
Publicado: (2022)

Evidence for an ABC-Type Riboflavin Transporter System in Pathogenic Spirochetes
por: Deka, Ranjit K., et al.
Publicado: (2013)

Biophysical and biochemical studies support TP0094 as a phosphotransacetylase in an acetogenic energy-conservation pathway in Treponema pallidum
por: Brautigam, Chad A., et al.
Publicado: (2023)

All about Internet FTP: learning and teaching to transfer files on the Internet
por: Robison, David F W
Publicado: (1994)

Functional and structural characterization of a flavoprotein monooxygenase essential for biogenesis of tryptophylquinone cofactor
por: Oozeki, Toshinori, et al.
Publicado: (2021)

Inequitable Distribution of FTP Marketing by Neighborhood Characteristics: Further Evidence for Targeted Marketing
por: Rose, Shyanika W, et al.
Publicado: (2021)

Flavin Adenine Dinucleotide Depletion Caused by electron transfer flavoprotein subunit alpha Haploinsufficiency Leads to Hepatic Steatosis and Injury in Zebrafish
por: Park, Ki‐Hoon, et al.
Publicado: (2021)

The reductive half-reaction of two bifurcating electron-transferring flavoproteins: Evidence for changes in flavin reduction potentials mediated by specific conformational changes
por: Vigil, Wayne, et al.
Publicado: (2022)

Fragmentation Through Polymerization (FTP): A new method to fragment DNA for next-generation sequencing
por: Ignatov, Konstantin B., et al.
Publicado: (2019)

Plant Flavoprotein Photoreceptors
por: Christie, John M., et al.
Publicado: (2015)

Spin Dynamics of Flavoproteins
por: Matysik, Jörg, et al.
Publicado: (2023)

Data of multilayer mesh NoC performance analysis for throughput and delay over FTP and CBR applications
por: Panem, Charanarur, et al.
Publicado: (2022)

Vertebrate Cryptochromes are Vestigial Flavoproteins
por: Kutta, Roger J., et al.
Publicado: (2017)

Cannabidiol sensitizes TRPV2 channels to activation by 2-APB
por: Gochman, Aaron, et al.
Publicado: (2023)

Flavin-mediated dual oxidation controls an enzymatic Favorskii-type rearrangement
por: Teufel, Robin, et al.
Publicado: (2013)

Barrier effect and wound healing activity of the medical device REF-FTP78 in the treatment of gastroesophageal reflux disease
por: Pecora, Tiziana M. G., et al.
Publicado: (2022)

Mechanism of Actin Filament Nucleation by the Bacterial Effector VopL
por: Yu, Bingke, et al.
Publicado: (2011)

An essential periplasmic protein coordinates lipid trafficking and is required for asymmetric polar growth in mycobacteria
por: Gupta, Kuldeepkumar R, et al.
Publicado: (2022)

Ferroptosis-Related Flavoproteins: Their Function and Stability
por: Vabulas, R. Martin
Publicado: (2021)

Straightforward Regeneration of Reduced Flavin Adenine Dinucleotide Required for Enzymatic Tryptophan Halogenation
por: Ismail, Mohamed, et al.
Publicado: (2019)

SAV1 promotes Hippo kinase activation through antagonizing the PP2A phosphatase STRIPAK
por: Bae, Sung Jun, et al.
Publicado: (2017)

Drofenine: a 2-APB analog with improved selectivity for human TRPV3
por: Deering-Rice, Cassandra E, et al.
Publicado: (2014)

Kinetic characterization of Vibrio cholerae ApbE: Substrate specificity and regulatory mechanisms
por: Fang, Xuan, et al.
Publicado: (2017)

Structural bases of TRP channel TRPV6 allosteric modulation by 2-APB
por: Singh, Appu K., et al.
Publicado: (2018)

Broadening the Scope of the Flavin‐Tag Method by Improving Flavin Incorporation and Incorporating Flavin Analogs
por: Tong, Yapei, et al.
Publicado: (2022)

BosR (BB0647) Controls the RpoN-RpoS Regulatory Pathway and Virulence Expression in Borrelia burgdorferi by a Novel DNA-Binding Mechanism
por: Ouyang, Zhiming, et al.
Publicado: (2011)

Mechanisms of Reaction of Some Flavoprotein Enzymes with Oxygen
por: Gibson, Quentin H.
Publicado: (1965)

Selective potentiation of 2-APB-induced activation of TRPV1–3 channels by acid
por: Gao, Luna, et al.
Publicado: (2016)

Detection and quantification of glycosylated queuosine modified tRNAs by acid denaturing and APB gels
por: Zhang, Wen, et al.
Publicado: (2020)

Human telomerase: biogenesis, trafficking, recruitment, and activation
por: Schmidt, Jens C., et al.
Publicado: (2015)

Biogenesis, Trafficking, and Function of Small RNAs in Plants
por: Tang, Yunjia, et al.
Publicado: (2022)

Editorial: Regulation of plant organelle biogenesis and trafficking
por: Neuhaus, Jean-Marc, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_4s7c43nvg0m7re1nmbkqk8n745