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Association Study of a Functional Variant on ABCG2 Gene with Sunitinib-Induced Severe Adverse Drug Reaction

Sunitinib is a tyrosine kinase inhibitor and used as the first-line treatment for advanced renal cell carcinoma (RCC). Nevertheless, inter-individual variability of drug’s toxicity was often observed among patients who received sunitinib treatment. This study is to investigate the association of a f...

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Detalles Bibliográficos
Autores principales: Low, Siew-Kee, Fukunaga, Koya, Takahashi, Atsushi, Matsuda, Koichi, Hongo, Fumiya, Nakanishi, Hiroyuki, Kitamura, Hiroshi, Inoue, Takamitsu, Kato, Yoichiro, Tomita, Yoshihiko, Fukasawa, Satoshi, Tanaka, Tomoaki, Nishimura, Kazuo, Uemura, Hirotsugu, Hara, Isao, Fujisawa, Masato, Matsuyama, Hideyasu, Hashine, Katsuyoshi, Tatsugami, Katsunori, Enokida, Hideki, Kubo, Michiaki, Miki, Tsuneharu, Mushiroda, Taisei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767438/
https://www.ncbi.nlm.nih.gov/pubmed/26914831
http://dx.doi.org/10.1371/journal.pone.0148177