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Stromal cell-mediated mitochondrial redox adaptation regulates drug resistance in childhood acute lymphoblastic leukemia
Despite the high cure rates in childhood acute lymphoblastic leukemia (ALL), relapsed ALL remains a significant clinical problem. Genetic heterogeneity does not adequately explain variations in response to therapy. The chemoprotective tumor microenvironment may additionally contribute to disease rec...
Autores principales: | Liu, Jizhong, Masurekar, Ashish, Johnson, Suzanne, Chakraborty, Sohini, Griffiths, John, Smith, Duncan, Alexander, Seema, Dempsey, Clare, Parker, Catriona, Harrison, Stephanie, Li, Yaoyong, Miller, Crispin, Di, Yujun, Ghosh, Zhumur, Krishnan, Shekhar, Saha, Vaskar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767490/ https://www.ncbi.nlm.nih.gov/pubmed/26474278 |
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