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An informatic framework for decoding protein complexes by top-down mass spectrometry
Efforts to map the human protein interactome have resulted in information about hundreds to thousands of multi-protein assemblies housed in public repositories, but the molecular characterization and stoichiometry of their protein subunits remains largely unknown. Here, we combined the CORUM and Uni...
Autores principales: | Skinner, Owen S., Havugimana, Pierre C., Haverland, Nicole A., Fornelli, Luca, Early, Bryan P., Greer, Joseph B., Fellers, Ryan T., Durbin, Kenneth R., Do Vale, Luis H. F., Melani, Rafael D., Seckler, Henrique S., Nelp, Micah T., Belov, Mikhail E., Horning, Stevan R., Makarov, Alexander A., LeDuc, Richard D., Bandarian, Vahe, Compton, Philip D., Kelleher, Neil L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767540/ https://www.ncbi.nlm.nih.gov/pubmed/26780093 http://dx.doi.org/10.1038/nmeth.3731 |
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