Cargando…

Nitric Oxide Protects against Infection-Induced Neuroinflammation by Preserving the Stability of the Blood-Brain Barrier

Nitric oxide (NO) generated by inducible NO synthase (iNOS) is critical for defense against intracellular pathogens but may mediate inflammatory tissue damage. To elucidate the role of iNOS in neuroinflammation, infections with encephalitogenic Trypanosoma brucei parasites were compared in inos (-/-...

Descripción completa

Detalles Bibliográficos
Autores principales:	Olivera, Gabriela C., Ren, Xiaoyuan, Vodnala, Suman K., Lu, Jun, Coppo, Lucia, Leepiyasakulchai, Chaniya, Holmgren, Arne, Kristensson, Krister, Rottenberg, Martin E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767601/ https://www.ncbi.nlm.nih.gov/pubmed/26915097 http://dx.doi.org/10.1371/journal.ppat.1005442

Ejemplares similares

Preclinical Assessment of the Treatment of Second-Stage African Trypanosomiasis with Cordycepin and Deoxycoformycin
por: Vodnala, Suman K., et al.
Publicado: (2009)

Circumventricular Organs and Parasite Neurotropism: Neglected Gates to the Brain?
por: Bentivoglio, Marina, et al.
Publicado: (2018)

Passage of parasites across the blood-brain barrier
por: Masocha, Willias, et al.
Publicado: (2012)

Tryps and trips: cell trafficking across the 100-year-old blood–brain barrier
por: Bentivoglio, Marina, et al.
Publicado: (2014)

Sensitive detection of the IS6110 sequence of Mycobacterium tuberculosis complex based on PCR-magnetic bead ELISA
por: Kyaw, Soe Paing, et al.
Publicado: (2018)

Synergistic antibacterial activity of silver with antibiotics correlating with the upregulation of the ROS production
por: Zou, Lili, et al.
Publicado: (2018)

Mycobacterium tuberculosis Infection Interferes with HIV Vaccination in Mice
por: Ignatowicz, Lech, et al.
Publicado: (2012)

Inhibition of the glutaredoxin and thioredoxin systems and ribonucleotide reductase by mutant p53-targeting compound APR-246
por: Haffo, Lena, et al.
Publicado: (2018)

Synergistic antibacterial effect of silver and ebselen against multidrug‐resistant Gram‐negative bacterial infections
por: Zou, Lili, et al.
Publicado: (2017)

Infection Rate and Tissue Localization of Murine IL-12p40-Producing Monocyte-Derived CD103(+) Lung Dendritic Cells during Pulmonary Tuberculosis
por: Leepiyasakulchai, Chaniya, et al.
Publicado: (2013)

Naturally-acquired cellular immune response against Plasmodium vivax merozoite surface protein-1 paralog antigen
por: Changrob, Siriruk, et al.
Publicado: (2015)

Potential role of viruses in neurodegeneration
por: Kristensson, Krister
Publicado: (1992)

Neuronal targeting and functional effects of infectious agents transmitted from animals to man
por: Kristensson, Krister
Publicado: (2003)

Interferon-γ signal drives differentiation of T-bet(hi) atypical memory B cells into plasma cells following Plasmodium vivax infection
por: Kochayoo, Piyawan, et al.
Publicado: (2022)

Toll-like receptor-mediated innate immune responses by recognition of the recombinant dormancy-associated Mycobacterium tuberculosis proteins Rv2659c and Rv1738
por: Saelee, Chutiphon, et al.
Publicado: (2022)

Increased sensitivity of enterotoxigenic Escherichia coli detection in stool samples using oligonucleotide immobilized-magnetic nanoparticles
por: Jangpatarapongsa, Kulachart, et al.
Publicado: (2021)

A substitution in the glutathione reductase lowers electron leakage and inflammation in modern humans
por: Coppo, Lucia, et al.
Publicado: (2022)

Nitric Oxide Influences HSV-1-Induced Neuroinflammation
por: Cymerys, Joanna, et al.
Publicado: (2019)

CD4(+) T-cell cooperation promoted pathogenic function of activated naïve B cells of patients with SLE
por: Wangriatisak, Kittikorn, et al.
Publicado: (2022)

Characterization of Duffy Binding Protein II-specific CD4(+)T cell responses in Plasmodium vivax patients
por: Thawornpan, Pongsakorn, et al.
Publicado: (2023)

The expansion of activated naive DNA autoreactive B cells and its association with disease activity in systemic lupus erythematosus patients
por: Wangriatisak, Kittikorn, et al.
Publicado: (2021)

Bioluminescent Imaging of Trypanosoma brucei Shows Preferential Testis Dissemination Which May Hamper Drug Efficacy in Sleeping Sickness
por: Claes, Filip, et al.
Publicado: (2009)

Targeting of endoplasmic reticulum-associated proteins to axons and dendrites in rotavirus-infected neurons
por: Weclewicz, Katarzyna, et al.
Publicado: (1998)

Lung infection by P. aeruginosa induces neuroinflammation and blood-brain barrier dysfunction in mice
por: Villalba, Nuria, et al.
Publicado: (2023)

Lung infection by Pseudomonas aeruginosa induces neuroinflammation and blood–brain barrier dysfunction in mice
por: Villalba, Nuria, et al.
Publicado: (2023)

Impaired cross-talk between the thioredoxin and glutathione systems is related to ASK-1 mediated apoptosis in neuronal cells exposed to mercury
por: Branco, Vasco, et al.
Publicado: (2017)

PECAM-1 Stabilizes Blood-Brain Barrier Integrity and Favors Paracellular T-Cell Diapedesis Across the Blood-Brain Barrier During Neuroinflammation
por: Wimmer, Isabella, et al.
Publicado: (2019)

Sero-surveillance for SARS-CoV-2 infection among healthcare providers in four hospitals in Thailand one year after the first community outbreak
por: Kittikraisak, Wanitchaya, et al.
Publicado: (2021)

A simple and fast method for fixation of cultured cell lines that preserves cellular structures containing gamma-tubulin
por: Alvarado-Kristensson, Maria
Publicado: (2018)

Regenerative Medicine Therapies for Targeting Neuroinflammation After Stroke
por: Rajkovic, Olivera, et al.
Publicado: (2018)

Impact of Metabolic Syndrome on Neuroinflammation and the Blood–Brain Barrier
por: Van Dyken, Peter, et al.
Publicado: (2018)

Role of Neuroinflammation and Blood-Brain Barrier Permutability on Migraine
por: Yamanaka, Gaku, et al.
Publicado: (2021)

Clusters of Drug-Resistant Mycobacterium tuberculosis Detected by Whole-Genome Sequence Analysis of Nationwide Sample, Thailand, 2014–2017
por: Nonghanphithak, Ditthawat, et al.
Publicado: (2021)

Gamma interferon expression and major histocompatibility complex induction during measles and vesicular stomatitis virus infections of the brain
por: Gogate, Nitin, et al.
Publicado: (1991)

Long-term association of a transcription factor with its chromatin binding site can stabilize gene expression and cell fate commitment
por: Gurdon, J. B., et al.
Publicado: (2020)

Thioredoxin 1 modulates apoptosis induced by bioactive compounds in prostate cancer cells
por: Rodriguez-Garcia, Aida, et al.
Publicado: (2017)

Nitric Oxide Signaling in Heart Failure With Preserved Ejection Fraction
por: Cruz, Lucas, et al.
Publicado: (2017)

Barriers and Advances in Kidney Preservation
por: Steichen, C., et al.
Publicado: (2018)

The Effects of Psychostimulant Drugs on Blood Brain Barrier Function and Neuroinflammation
por: Kousik, Sharanya M., et al.
Publicado: (2012)

Imaging blood–brain barrier disruption in neuroinflammation and Alzheimer’s disease
por: Lee, Rae-Ling, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_bh692ok6u1p4iiuui7u8fv705e