Integrative genomic analysis by interoperation of bioinformatics tools in GenomeSpace

Integrative analysis of multiple data types to address complex biomedical questions requires the use of multiple software tools in concert and remains an enormous challenge for most of the biomedical research community. Here we introduce GenomeSpace (http://www.genomespace.org), a cloud-based, coope...

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Autores principales: Qu, Kun, Garamszegi, Sara, Wu, Felix, Thorvaldsdottir, Helga, Liefeld, Ted, Ocana, Marco, Borges-Rivera, Diego, Pochet, Nathalie, Robinson, James T., Demchak, Barry, Hull, Tim, Ben-Artzi, Gil, Blankenberg, Daniel, Barber, Galt P., Lee, Brian T., Kuhn, Robert M., Nekrutenko, Anton, Segal, Eran, Ideker, Trey, Reich, Michael, Regev, Aviv, Chang, Howard Y., Mesirov, Jill P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767623/
https://www.ncbi.nlm.nih.gov/pubmed/26780094
http://dx.doi.org/10.1038/nmeth.3732
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author Qu, Kun
Garamszegi, Sara
Wu, Felix
Thorvaldsdottir, Helga
Liefeld, Ted
Ocana, Marco
Borges-Rivera, Diego
Pochet, Nathalie
Robinson, James T.
Demchak, Barry
Hull, Tim
Ben-Artzi, Gil
Blankenberg, Daniel
Barber, Galt P.
Lee, Brian T.
Kuhn, Robert M.
Nekrutenko, Anton
Segal, Eran
Ideker, Trey
Reich, Michael
Regev, Aviv
Chang, Howard Y.
Mesirov, Jill P.
author_facet Qu, Kun
Garamszegi, Sara
Wu, Felix
Thorvaldsdottir, Helga
Liefeld, Ted
Ocana, Marco
Borges-Rivera, Diego
Pochet, Nathalie
Robinson, James T.
Demchak, Barry
Hull, Tim
Ben-Artzi, Gil
Blankenberg, Daniel
Barber, Galt P.
Lee, Brian T.
Kuhn, Robert M.
Nekrutenko, Anton
Segal, Eran
Ideker, Trey
Reich, Michael
Regev, Aviv
Chang, Howard Y.
Mesirov, Jill P.
author_sort Qu, Kun
collection PubMed
description Integrative analysis of multiple data types to address complex biomedical questions requires the use of multiple software tools in concert and remains an enormous challenge for most of the biomedical research community. Here we introduce GenomeSpace (http://www.genomespace.org), a cloud-based, cooperative community resource. Seeded as a collaboration of six of the most popular genomics analysis tools, GenomeSpace now supports the streamlined interaction of 20 bioinformatics tools and data resources. To facilitate the ability of non-programming users’ to leverage GenomeSpace in integrative analysis, it offers a growing set of ‘recipes’, short workflows involving a few tools and steps to guide investigators through high utility analysis tasks.
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spelling pubmed-47676232016-07-18 Integrative genomic analysis by interoperation of bioinformatics tools in GenomeSpace Qu, Kun Garamszegi, Sara Wu, Felix Thorvaldsdottir, Helga Liefeld, Ted Ocana, Marco Borges-Rivera, Diego Pochet, Nathalie Robinson, James T. Demchak, Barry Hull, Tim Ben-Artzi, Gil Blankenberg, Daniel Barber, Galt P. Lee, Brian T. Kuhn, Robert M. Nekrutenko, Anton Segal, Eran Ideker, Trey Reich, Michael Regev, Aviv Chang, Howard Y. Mesirov, Jill P. Nat Methods Article Integrative analysis of multiple data types to address complex biomedical questions requires the use of multiple software tools in concert and remains an enormous challenge for most of the biomedical research community. Here we introduce GenomeSpace (http://www.genomespace.org), a cloud-based, cooperative community resource. Seeded as a collaboration of six of the most popular genomics analysis tools, GenomeSpace now supports the streamlined interaction of 20 bioinformatics tools and data resources. To facilitate the ability of non-programming users’ to leverage GenomeSpace in integrative analysis, it offers a growing set of ‘recipes’, short workflows involving a few tools and steps to guide investigators through high utility analysis tasks. 2016-01-18 2016-03 /pmc/articles/PMC4767623/ /pubmed/26780094 http://dx.doi.org/10.1038/nmeth.3732 Text en Users may view, print, copy, and download text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use:http://www.nature.com/authors/editorial_policies/license.html#terms
spellingShingle Article
Qu, Kun
Garamszegi, Sara
Wu, Felix
Thorvaldsdottir, Helga
Liefeld, Ted
Ocana, Marco
Borges-Rivera, Diego
Pochet, Nathalie
Robinson, James T.
Demchak, Barry
Hull, Tim
Ben-Artzi, Gil
Blankenberg, Daniel
Barber, Galt P.
Lee, Brian T.
Kuhn, Robert M.
Nekrutenko, Anton
Segal, Eran
Ideker, Trey
Reich, Michael
Regev, Aviv
Chang, Howard Y.
Mesirov, Jill P.
Integrative genomic analysis by interoperation of bioinformatics tools in GenomeSpace
title Integrative genomic analysis by interoperation of bioinformatics tools in GenomeSpace
title_full Integrative genomic analysis by interoperation of bioinformatics tools in GenomeSpace
title_fullStr Integrative genomic analysis by interoperation of bioinformatics tools in GenomeSpace
title_full_unstemmed Integrative genomic analysis by interoperation of bioinformatics tools in GenomeSpace
title_short Integrative genomic analysis by interoperation of bioinformatics tools in GenomeSpace
title_sort integrative genomic analysis by interoperation of bioinformatics tools in genomespace
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767623/
https://www.ncbi.nlm.nih.gov/pubmed/26780094
http://dx.doi.org/10.1038/nmeth.3732
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