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Effects of Fostamatinib on the Pharmacokinetics of Oral Contraceptive, Warfarin, and the Statins Rosuvastatin and Simvastatin: Results From Phase I Clinical Studies

BACKGROUND AND OBJECTIVES: Fostamatinib is a spleen tyrosine kinase inhibitor that has been investigated as therapy for rheumatoid arthritis and immune thrombocytopenic purpura. The present studies assessed the potential for pharmacokinetic interaction between fostamatinib and the commonly prescribe...

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Detalles Bibliográficos
Autores principales:	Martin, P., Gillen, M., Ritter, J., Mathews, D., Brealey, C., Surry, D., Oliver, S., Holmes, V., Severin, P., Elsby, R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2016
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767723/ https://www.ncbi.nlm.nih.gov/pubmed/26748647 http://dx.doi.org/10.1007/s40268-015-0120-x

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