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Venous thromboembolism after radical cystectomy: Experience with screening ultrasonography
OBJECTIVES: To detect the incidence of immediate postoperative deep vein thrombosis (DVT) using screening lower extremity ultrasonography (US) in patients undergoing radical cystectomy (RC) and to determine the rate of symptomatic pulmonary embolism (PE) after RC and identify risk factors for venous...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767786/ https://www.ncbi.nlm.nih.gov/pubmed/26966592 http://dx.doi.org/10.1016/j.aju.2015.11.002 |
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author | Murray, Katie M. Parker, William Stephany, Heidi Redger, Kirk Mirza, Moben Lopez-Corona, Ernesto Holzbeierlein, Jeffrey M. Lee, Eugene K. |
author_facet | Murray, Katie M. Parker, William Stephany, Heidi Redger, Kirk Mirza, Moben Lopez-Corona, Ernesto Holzbeierlein, Jeffrey M. Lee, Eugene K. |
author_sort | Murray, Katie M. |
collection | PubMed |
description | OBJECTIVES: To detect the incidence of immediate postoperative deep vein thrombosis (DVT) using screening lower extremity ultrasonography (US) in patients undergoing radical cystectomy (RC) and to determine the rate of symptomatic pulmonary embolism (PE) after RC and identify risk factors for venous thromboembolic (VTE) events in a RC population. PATIENTS AND METHODS: We performed a retrospective review of prospective data collected on patients who underwent RC between July 2008 and January 2012. These patients underwent screening US at 2/3 days after RC to determine the rate of asymptomatic DVT. A chart review was completed to identify those who had a symptomatic PE. Univariate and multivariable analysis was used to identify risk factors associated with DVT, PE and total VTE events. RESULTS: In all, 221 patients underwent RC and asymptomatic DVT was identified in 21 (9.5%) on screening US. Nine (4.5%) developed symptomatic PE at a median of 9 days, of which no patients had positive lower extremity US postoperatively. Increased length of hospital stay, increased estimated blood loss, and lower body mass index were linked to risk of PE, and only a previous history of DVT was associated with postoperative DVT. CONCLUSION: Patients who undergo RC are at high-risk for thromboembolic events and multimodal prophylaxis should be administered. Clinicians should be especially vigilant in those who demonstrate factors associated with higher risk for VTE events. |
format | Online Article Text |
id | pubmed-4767786 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-47677862016-03-10 Venous thromboembolism after radical cystectomy: Experience with screening ultrasonography Murray, Katie M. Parker, William Stephany, Heidi Redger, Kirk Mirza, Moben Lopez-Corona, Ernesto Holzbeierlein, Jeffrey M. Lee, Eugene K. Arab J Urol Oncology/Reconstruction Original article OBJECTIVES: To detect the incidence of immediate postoperative deep vein thrombosis (DVT) using screening lower extremity ultrasonography (US) in patients undergoing radical cystectomy (RC) and to determine the rate of symptomatic pulmonary embolism (PE) after RC and identify risk factors for venous thromboembolic (VTE) events in a RC population. PATIENTS AND METHODS: We performed a retrospective review of prospective data collected on patients who underwent RC between July 2008 and January 2012. These patients underwent screening US at 2/3 days after RC to determine the rate of asymptomatic DVT. A chart review was completed to identify those who had a symptomatic PE. Univariate and multivariable analysis was used to identify risk factors associated with DVT, PE and total VTE events. RESULTS: In all, 221 patients underwent RC and asymptomatic DVT was identified in 21 (9.5%) on screening US. Nine (4.5%) developed symptomatic PE at a median of 9 days, of which no patients had positive lower extremity US postoperatively. Increased length of hospital stay, increased estimated blood loss, and lower body mass index were linked to risk of PE, and only a previous history of DVT was associated with postoperative DVT. CONCLUSION: Patients who undergo RC are at high-risk for thromboembolic events and multimodal prophylaxis should be administered. Clinicians should be especially vigilant in those who demonstrate factors associated with higher risk for VTE events. Elsevier 2016-03 2015-12-29 /pmc/articles/PMC4767786/ /pubmed/26966592 http://dx.doi.org/10.1016/j.aju.2015.11.002 Text en © 2015 Arab Association of Urology. Production and hosting by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Oncology/Reconstruction Original article Murray, Katie M. Parker, William Stephany, Heidi Redger, Kirk Mirza, Moben Lopez-Corona, Ernesto Holzbeierlein, Jeffrey M. Lee, Eugene K. Venous thromboembolism after radical cystectomy: Experience with screening ultrasonography |
title | Venous thromboembolism after radical cystectomy: Experience with screening ultrasonography |
title_full | Venous thromboembolism after radical cystectomy: Experience with screening ultrasonography |
title_fullStr | Venous thromboembolism after radical cystectomy: Experience with screening ultrasonography |
title_full_unstemmed | Venous thromboembolism after radical cystectomy: Experience with screening ultrasonography |
title_short | Venous thromboembolism after radical cystectomy: Experience with screening ultrasonography |
title_sort | venous thromboembolism after radical cystectomy: experience with screening ultrasonography |
topic | Oncology/Reconstruction Original article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767786/ https://www.ncbi.nlm.nih.gov/pubmed/26966592 http://dx.doi.org/10.1016/j.aju.2015.11.002 |
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