Clonidine increases bone resorption in humans

SUMMARY: Inhibition of sympathetic signaling to bone reduces bone resorption in rodents. In contrast, we show that pharmacological reduction of the sympathetic tone increases bone resorption in humans in vivo. This effect does not appear to be mediated via a direct pharmacological effect on the oste...

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Detalles Bibliográficos
Autores principales: Limonard, E. J., Schoenmaker, T., de Vries, T. J., Tanck, M. W., Heijboer, A. C., Endert, E., Fliers, E., Everts, V., Bisschop, P. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer London 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767867/
https://www.ncbi.nlm.nih.gov/pubmed/26439240
http://dx.doi.org/10.1007/s00198-015-3312-x

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