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Stochastic SIR epidemics in a population with households and schools

We study the spread of stochastic SIR (Susceptible [Formula: see text] Infectious [Formula: see text] Recovered) epidemics in two types of structured populations, both consisting of schools and households. In each of the types, every individual is part of one school and one household. In the indepen...

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Detalles Bibliográficos
Autores principales: Ouboter, Tanneke, Meester, Ronald, Trapman, Pieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767871/
https://www.ncbi.nlm.nih.gov/pubmed/26070348
http://dx.doi.org/10.1007/s00285-015-0901-4
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author Ouboter, Tanneke
Meester, Ronald
Trapman, Pieter
author_facet Ouboter, Tanneke
Meester, Ronald
Trapman, Pieter
author_sort Ouboter, Tanneke
collection PubMed
description We study the spread of stochastic SIR (Susceptible [Formula: see text] Infectious [Formula: see text] Recovered) epidemics in two types of structured populations, both consisting of schools and households. In each of the types, every individual is part of one school and one household. In the independent partition model, the partitions of the population into schools and households are independent of each other. This model corresponds to the well-studied household-workplace model. In the hierarchical model which we introduce here, members of the same household are also members of the same school. We introduce computable branching process approximations for both types of populations and use these to compare the probabilities of a large outbreak. The branching process approximation in the hierarchical model is novel and of independent interest. We prove by a coupling argument that if all households and schools have the same size, an epidemic spreads easier (in the sense that the number of individuals infected is stochastically larger) in the independent partition model. We also show by example that this result does not necessarily hold if households and/or schools do not all have the same size.
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spelling pubmed-47678712016-03-29 Stochastic SIR epidemics in a population with households and schools Ouboter, Tanneke Meester, Ronald Trapman, Pieter J Math Biol Article We study the spread of stochastic SIR (Susceptible [Formula: see text] Infectious [Formula: see text] Recovered) epidemics in two types of structured populations, both consisting of schools and households. In each of the types, every individual is part of one school and one household. In the independent partition model, the partitions of the population into schools and households are independent of each other. This model corresponds to the well-studied household-workplace model. In the hierarchical model which we introduce here, members of the same household are also members of the same school. We introduce computable branching process approximations for both types of populations and use these to compare the probabilities of a large outbreak. The branching process approximation in the hierarchical model is novel and of independent interest. We prove by a coupling argument that if all households and schools have the same size, an epidemic spreads easier (in the sense that the number of individuals infected is stochastically larger) in the independent partition model. We also show by example that this result does not necessarily hold if households and/or schools do not all have the same size. Springer Berlin Heidelberg 2015-06-13 2016 /pmc/articles/PMC4767871/ /pubmed/26070348 http://dx.doi.org/10.1007/s00285-015-0901-4 Text en © The Author(s) 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Article
Ouboter, Tanneke
Meester, Ronald
Trapman, Pieter
Stochastic SIR epidemics in a population with households and schools
title Stochastic SIR epidemics in a population with households and schools
title_full Stochastic SIR epidemics in a population with households and schools
title_fullStr Stochastic SIR epidemics in a population with households and schools
title_full_unstemmed Stochastic SIR epidemics in a population with households and schools
title_short Stochastic SIR epidemics in a population with households and schools
title_sort stochastic sir epidemics in a population with households and schools
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767871/
https://www.ncbi.nlm.nih.gov/pubmed/26070348
http://dx.doi.org/10.1007/s00285-015-0901-4
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