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Phenotypic Characterization of a Novel Virulence-Factor Deletion Strain of Burkholderia mallei That Provides Partial Protection against Inhalational Glanders in Mice

Burkholderia mallei (Bm) is a highly infectious intracellular pathogen classified as a category B biological agent by the Centers for Disease Control and Prevention. After respiratory exposure, Bm establishes itself within host macrophages before spreading into major organ systems, which can lead to...

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Detalles Bibliográficos
Autores principales: Bozue, Joel A., Chaudhury, Sidhartha, Amemiya, Kei, Chua, Jennifer, Cote, Christopher K., Toothman, Ronald G., Dankmeyer, Jennifer L., Klimko, Christopher P., Wilhelmsen, Catherine L., Raymond, Jolynn W., Zavaljevski, Nela, Reifman, Jaques, Wallqvist, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767903/
https://www.ncbi.nlm.nih.gov/pubmed/26955620
http://dx.doi.org/10.3389/fcimb.2016.00021