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Phenotypic Characterization of a Novel Virulence-Factor Deletion Strain of Burkholderia mallei That Provides Partial Protection against Inhalational Glanders in Mice
Burkholderia mallei (Bm) is a highly infectious intracellular pathogen classified as a category B biological agent by the Centers for Disease Control and Prevention. After respiratory exposure, Bm establishes itself within host macrophages before spreading into major organ systems, which can lead to...
Autores principales: | Bozue, Joel A., Chaudhury, Sidhartha, Amemiya, Kei, Chua, Jennifer, Cote, Christopher K., Toothman, Ronald G., Dankmeyer, Jennifer L., Klimko, Christopher P., Wilhelmsen, Catherine L., Raymond, Jolynn W., Zavaljevski, Nela, Reifman, Jaques, Wallqvist, Anders |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767903/ https://www.ncbi.nlm.nih.gov/pubmed/26955620 http://dx.doi.org/10.3389/fcimb.2016.00021 |
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