Stiff substrates increase YAP-signaling-mediated matrix metalloproteinase-7 expression

Abnormally stiff substrates have been shown to trigger cancer progression. However, the detailed molecular mechanisms underlying this trigger are not clear. In this study, we cultured T84 human colorectal cancer cells on plastic dishes to create a stiff substrate or on collagen-I gel to create a sof...

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Detalles Bibliográficos
Autores principales: Nukuda, A, Sasaki, C, Ishihara, S, Mizutani, T, Nakamura, K, Ayabe, T, Kawabata, K, Haga, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767936/
https://www.ncbi.nlm.nih.gov/pubmed/26344692
http://dx.doi.org/10.1038/oncsis.2015.24

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