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Viral Escape Mutant Epitope Maintains TCR Affinity for Antigen yet Curtails CD8 T Cell Responses

T cells have the remarkable ability to recognize antigen with great specificity and in turn mount an appropriate and robust immune response. Critical to this process is the initial T cell antigen recognition and subsequent signal transduction events. This antigen recognition can be modulated at the...

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Detalles Bibliográficos
Autores principales:	Shorter, Shayla K., Schnell, Frederick J., McMaster, Sean R., Pinelli, David F., Andargachew, Rakieb, Evavold, Brian D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767940/ https://www.ncbi.nlm.nih.gov/pubmed/26915099 http://dx.doi.org/10.1371/journal.pone.0149582

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