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Regulatory T cells inhibit CD34+ cell differentiation into NK cells by blocking their proliferation

Graft versus Host Disease (GvHD) remains one of the main complications after hematopoietic stem cell transplantation (HSCT). Due to their ability to suppress effector cells, regulatory T cells (Tregs) have been proposed as a cellular therapy to prevent GvHD, however they also inhibit the functions o...

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Detalles Bibliográficos
Autores principales: Pedroza-Pacheco, Isabela, Shah, Divya, Domogala, Anna, Luevano, Martha, Blundell, Michael, Jackson, Nicola, Thrasher, Adrian, Madrigal, Alejandro, Saudemont, Aurore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768165/
https://www.ncbi.nlm.nih.gov/pubmed/26915707
http://dx.doi.org/10.1038/srep22097