Cargando…

Regulatory T cells inhibit CD34+ cell differentiation into NK cells by blocking their proliferation

Graft versus Host Disease (GvHD) remains one of the main complications after hematopoietic stem cell transplantation (HSCT). Due to their ability to suppress effector cells, regulatory T cells (Tregs) have been proposed as a cellular therapy to prevent GvHD, however they also inhibit the functions o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pedroza-Pacheco, Isabela, Shah, Divya, Domogala, Anna, Luevano, Martha, Blundell, Michael, Jackson, Nicola, Thrasher, Adrian, Madrigal, Alejandro, Saudemont, Aurore
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768165/ https://www.ncbi.nlm.nih.gov/pubmed/26915707 http://dx.doi.org/10.1038/srep22097

Ejemplares similares

Frozen Cord Blood Hematopoietic Stem Cells Differentiate into Higher Numbers of Functional Natural Killer Cells In Vitro than Mobilized Hematopoietic Stem Cells or Freshly Isolated Cord Blood Hematopoietic Stem Cells
por: Luevano, Martha, et al.
Publicado: (2014)

Natural Killer Cell Immunotherapy: From Bench to Bedside
por: Domogala, Anna, et al.
Publicado: (2015)

Transcription factors involved in the regulation of natural killer cell development and function: an update
por: Luevano, Martha, et al.
Publicado: (2012)

Natural Killer Cells Improve Hematopoietic Stem Cell Engraftment by Increasing Stem Cell Clonogenicity In Vitro and in a Humanized Mouse Model
por: Escobedo-Cousin, Michelle, et al.
Publicado: (2015)

The Effects of CAMPATH-1H on Cell Viability Do Not Correlate to the CD52 Density on the Cell Surface
por: Lee, Fuiyee, et al.
Publicado: (2014)

Clinical Grade Regulatory CD4(+) T Cells (Tregs): Moving Toward Cellular-Based Immunomodulatory Therapies
por: Duggleby, Richard, et al.
Publicado: (2018)

B cell regulation in cancer and anti-tumor immunity
por: Sarvaria, Anushruti, et al.
Publicado: (2017)

Umbilical Cord Blood Natural Killer Cells, Their Characteristics, and Potential Clinical Applications
por: Sarvaria, Anushruti, et al.
Publicado: (2017)

Subordinate Effect of -21M HLA-B Dimorphism on NK Cell Repertoire Diversity and Function in HIV-1 Infected Individuals of African Origin
por: Cubero, Elia Moreno, et al.
Publicado: (2020)

Current Status of Gene Engineering Cell Therapeutics
por: Saudemont, Aurore, et al.
Publicado: (2018)

Regulatory NK cells in autoimmune disease
por: Bahadorian, Davood, et al.
Publicado: (2023)

Generation of a Novel Regulatory NK Cell Subset from Peripheral Blood CD34(+) Progenitors Promoted by Membrane-Bound IL-15
por: Giuliani, Massimo, et al.
Publicado: (2008)

Regulatory effects of dexamethasone on NK and T cell immunity
por: Chen, Liying, et al.
Publicado: (2017)

Inhibition of Glucose Uptake Blocks Proliferation but Not Cytotoxic Activity of NK Cells
por: Picard, Lea Katharina, et al.
Publicado: (2022)

Functional Characterisation and Analysis of the Soluble NKG2D Ligand Repertoire Detected in Umbilical Cord Blood Plasma
por: Cox, Steven T., et al.
Publicado: (2018)

Corrigendum: Functional Characterisation and Analysis of the Soluble NKG2D Ligand Repertoire Detected in Umbilical Cord Blood Plasma
por: Cox, Steven T., et al.
Publicado: (2020)

Intratumor Regulatory Noncytotoxic NK Cells in Patients with Hepatocellular Carcinoma
por: Zecca, Alessandra, et al.
Publicado: (2021)

Preeclampsia is Characterized by Fetal NK Cell Activation and a Reduction in Regulatory T Cells
por: Loewendorf, Andrea I., et al.
Publicado: (2015)

IL-10(+) NK and TGF-β(+) NK cells play negative regulatory roles in HIV infection
por: Jiang, Yongjun, et al.
Publicado: (2018)

IL-2–dependent tuning of NK cell sensitivity for target cells is controlled by regulatory T cells
por: Gasteiger, Georg, et al.
Publicado: (2013)

Regulatory T cells control NK cells in an insulitic lesion by depriving them of IL-2
por: Sitrin, Jonathan, et al.
Publicado: (2013)

Populations of NK Cells and Regulatory T Cells in the Endometrium of Cycling Mares—A Preliminary Study
por: Jaworska, Joanna, et al.
Publicado: (2022)

Activation of Cytotoxic and Regulatory Functions of NK Cells by Sindbis Viral Vectors
por: Granot, Tomer, et al.
Publicado: (2011)

The Wiskott-Aldrich Syndrome: The Actin Cytoskeleton and Immune Cell Function
por: Blundell, Michael P., et al.
Publicado: (2010)

Adaptive Reconfiguration of Natural Killer Cells in HIV-1 Infection
por: Peppa, Dimitra, et al.
Publicado: (2018)

In vitro generation of allo-reactive human NK cells from umblillical cord blood CD34+ progenitor cells
por: Ahn, Yong-Oon, et al.
Publicado: (2015)

Early TRAIL-engagement elicits potent multimodal targeting of melanoma by CD34(+) progenitor cell-derived NK cells
por: van Vliet, Amanda A., et al.
Publicado: (2023)

Dominant cytotoxic NK cell subset within CLPD-NK patients identifies a more aggressive NK cell proliferation
por: Barilà, Gregorio, et al.
Publicado: (2018)

Targeting autoantibodies in COVID-19
por: Pedroza-Pacheco, Isabela, et al.
Publicado: (2021)

Regulatory NK cells mediated between immunosuppressive monocytes and dysfunctional T cells in chronic HBV infection
por: Li, Haijun, et al.
Publicado: (2018)

Response of human natural killer (NK) cells to NK cell stimulatory factor (NKSF): cytolytic activity and proliferation of NK cells are differentially regulated by NKSF
Publicado: (1992)

Mechanisms of Resistance to NK Cell Immunotherapy
por: Sordo-Bahamonde, Christian, et al.
Publicado: (2020)

T-cell suppression mediated by regulatory T cells infiltrating hepatic tumors can be overcome by GITRL treatment
por: Pedroza-Gonzalez, Alexander, et al.
Publicado: (2013)

High Fructose Negatively Impacts Proliferation of NSC-34 Motor Neuron Cell Line
por: Lodha, Divya, et al.
Publicado: (2022)

Interleukin-21 induces the differentiation of human umbilical cord blood CD34(-)lineage(- )cells into pseudomature lytic NK cells
por: Bonanno, Giuseppina, et al.
Publicado: (2009)

Challenges and Prospects for Designer T and NK Cells in Glioblastoma Immunotherapy
por: Arnesen, Victoria Smith, et al.
Publicado: (2021)

TATTOO-seq delineates spatial and cell type–specific regulatory programs in the developing limb
por: Bastide, Sébastien, et al.
Publicado: (2022)

Blocking HIF to Enhance NK Cells: Hints for New Anti-Tumor Therapeutic Strategies?
por: Vitale, Massimo, et al.
Publicado: (2021)

Blocking the PCNA/NKp44 Checkpoint to Stimulate NK Cell Responses to Multiple Myeloma
por: Iraqi, Muhammed, et al.
Publicado: (2022)

NK-cell fratricide: Dynamic crosstalk between NK and cancer cells
por: Nakamura, Kyohei, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_tmbr135800fob8dujv53ukbau9