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Targeting surface-layer proteins with single-domain antibodies: a potential therapeutic approach against Clostridium difficile-associated disease

Clostridium difficile is a leading cause of death from gastrointestinal infections in North America. Antibiotic therapy is effective, but the high incidence of relapse and the rise in hypervirulent strains warrant the search for novel treatments. Surface layer proteins (SLPs) cover the entire C. dif...

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Detalles Bibliográficos
Autores principales:	Kandalaft, Hiba, Hussack, Greg, Aubry, Annie, van Faassen, Henk, Guan, Yonghong, Arbabi-Ghahroudi, Mehdi, MacKenzie, Roger, Logan, Susan M., Tanha, Jamshid
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2015
Materias:	Biotechnologically Relevant Enzymes and Proteins
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768215/ https://www.ncbi.nlm.nih.gov/pubmed/25936376 http://dx.doi.org/10.1007/s00253-015-6594-1

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