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Prognostic Impact of Modulators of G proteins in Circulating Tumor Cells from Patients with Metastatic Colorectal Cancer

The consequence of a loss of balance between G-protein activation and deactivation in cancers has been interrogated by studying infrequently occurring mutants of trimeric G-protein α-subunits and GPCRs. Prior studies on members of a newly identified family of non-receptor guanine nucleotide exchange...

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Detalles Bibliográficos
Autores principales: Barbazan, Jorge, Dunkel, Ying, Li, Hongying, Nitsche, Ulrich, Janssen, Klaus-Peter, Messer, Karen, Ghosh, Pradipta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768264/
https://www.ncbi.nlm.nih.gov/pubmed/26916336
http://dx.doi.org/10.1038/srep22112