Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation

The study of biliary disease has been constrained by a lack of primary human cholangiocytes. Here we present an efficient, serum-free protocol for directed differentiation of human induced pluripotent stem cells into cholangiocyte-like cells (CLCs). CLCs show functional characteristics of cholangioc...

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Detalles Bibliográficos
Autores principales: Sampaziotis, Fotios, de Brito, Miguel Cardoso, Madrigal, Pedro, Bertero, Alessandro, Saeb-Parsy, Kourosh, Soares, Filipa A. C., Schrumpf, Elisabeth, Melum, Espen, Karlsen, Tom H., Bradley, J. Andrew, Gelson, William TH, Davies, Susan, Baker, Alastair, Kaser, Arthur, Alexander, Graeme J., Hannan, Nicholas R.F., Vallier, Ludovic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768345/
https://www.ncbi.nlm.nih.gov/pubmed/26167629
http://dx.doi.org/10.1038/nbt.3275

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