Dual roles of the adenosine A2a receptor in autoimmune neuroinflammation

BACKGROUND: Conditions of inflammatory tissue distress are associated with high extracellular levels of adenosine, due to increased adenosine triphosphate (ATP) degradation upon cellular stress or the release of extracellular ATP upon cell death, which can be degraded to adenosine by membrane-bound...

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Detalles Bibliográficos
Autores principales: Ingwersen, J., Wingerath, B., Graf, J., Lepka, K., Hofrichter, M., Schröter, F., Wedekind, F., Bauer, A., Schrader, J., Hartung, H.-P., Prozorovski, T., Aktas, O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768407/
https://www.ncbi.nlm.nih.gov/pubmed/26920550
http://dx.doi.org/10.1186/s12974-016-0512-z

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