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Intravenous immune globulin suppresses angiogenesis in mice and humans
Human intravenous immune globulin (IVIg), a purified IgG fraction composed of ~60% IgG1 and obtained from the pooled plasma of thousands of donors, is clinically used for a wide range of diseases. The biological actions of IVIg are incompletely understood and have been attributed both to the polyclo...
Autores principales: | Yasuma, Reo, Cicatiello, Valeria, Mizutani, Takeshi, Tudisco, Laura, Kim, Younghee, Tarallo, Valeria, Bogdanovich, Sasha, Hirano, Yoshio, Kerur, Nagaraj, Li, Shengjian, Yasuma, Tetsuhiro, Fowler, Benjamin J, Wright, Charles B, Apicella, Ivana, Greco, Adelaide, Brunetti, Arturo, Ambati, Balamurali K, Helmers, Sevim Barbasso, Lundberg, Ingrid E, Viklicky, Ondrej, Leusen, Jeanette HW, Verbeek, J Sjef, Gelfand, Bradley D, Bastos-Carvalho, Ana, De Falco, Sandro, Ambati, Jayakrishna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768485/ https://www.ncbi.nlm.nih.gov/pubmed/26925256 http://dx.doi.org/10.1038/sigtrans.2015.2 |
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