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A Multi‐RNAi Microsponge Platform for Simultaneous Controlled Delivery of Multiple Small Interfering RNAs
Packaging multiple small interfering RNA (siRNA) molecules into nanostructures at precisely defined ratios is a powerful delivery strategy for effective RNA interference (RNAi) therapy. We present a novel RNA nanotechnology based approach to produce multiple components of polymerized siRNA molecules...
Autores principales: | Roh, Young Hoon, Deng, Jason Z., Dreaden, Erik C., Park, Jae Hyon, Yun, Dong Soo, Shopsowitz, Kevin E., Hammond, Paula T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768639/ https://www.ncbi.nlm.nih.gov/pubmed/26695874 http://dx.doi.org/10.1002/anie.201508978 |
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