Cargando…

A Multi‐RNAi Microsponge Platform for Simultaneous Controlled Delivery of Multiple Small Interfering RNAs

Packaging multiple small interfering RNA (siRNA) molecules into nanostructures at precisely defined ratios is a powerful delivery strategy for effective RNA interference (RNAi) therapy. We present a novel RNA nanotechnology based approach to produce multiple components of polymerized siRNA molecules...

Descripción completa

Detalles Bibliográficos
Autores principales:	Roh, Young Hoon, Deng, Jason Z., Dreaden, Erik C., Park, Jae Hyon, Yun, Dong Soo, Shopsowitz, Kevin E., Hammond, Paula T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2015
Materias:	Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768639/ https://www.ncbi.nlm.nih.gov/pubmed/26695874 http://dx.doi.org/10.1002/anie.201508978

Ejemplares similares

Layer-by-Layer Assembled Antisense DNA Microsponge Particles for Efficient Delivery of Cancer Therapeutics
por: Roh, Young Hoon, et al.
Publicado: (2014)

A Convergent Synthetic Platform for Single-Nanoparticle Combination Cancer Therapy: Ratiometric Loading and Controlled Release of Cisplatin, Doxorubicin, and Camptothecin
por: Liao, Longyan, et al.
Publicado: (2014)

Periodic-shRNA molecules are capable of gene silencing, cytotoxicity and innate immune activation in cancer cells
por: Shopsowitz, Kevin E., et al.
Publicado: (2016)

Combinatorial delivery of small interfering RNAs reduces RNAi efficacy by selective incorporation into RISC
por: Castanotto, Daniela, et al.
Publicado: (2007)

Microsponges: A novel strategy for drug delivery system
por: Kaity, Santanu, et al.
Publicado: (2010)

In Vivo Delivery of RNAi by Reducible Interfering Nanoparticles (iNOPs)
por: Baigude, Huricha, et al.
Publicado: (2013)

Formulation and Evaluation of Optimized Oxybenzone Microsponge Gel for Topical Delivery
por: Pawar, Atmaram P., et al.
Publicado: (2015)

Formulation and evaluation of curcumin microsponges for oral and topical drug delivery
por: Bhatia, Meenakshi, et al.
Publicado: (2018)

Bimodal Tumor-Targeting from Microenvironment Responsive Hyaluronan Layer-by-Layer (LbL) Nanoparticles
por: Dreaden, Erik C., et al.
Publicado: (2014)

Fabrication, characterization, and evaluation of microsponge delivery system for facilitated fungal therapy
por: Moin, Afrasim, et al.
Publicado: (2016)

Microsponges based novel drug delivery system for augmented arthritis therapy
por: Osmani, Riyaz Ali M., et al.
Publicado: (2015)

Nanoporous Microsponge Particles (NMP) of Polysaccharides as Universal Carriers for Biomolecules Delivery
por: Caso, Maria Federica, et al.
Publicado: (2020)

Microsponges for dermatological applications: Perspectives and challenges
por: Mahant, Sheefali, et al.
Publicado: (2020)

Fabrication and Characterization of Sertaconazole Nitrate Microsponge as a Topical Drug Delivery System
por: Pande, V. V., et al.
Publicado: (2015)

Alginate Microsponges as a Scaffold for Delivery of a Therapeutic Peptide against Rheumatoid Arthritis
por: Ariaudo, Daniela, et al.
Publicado: (2023)

Ocular administration of acetazolamide microsponges in situ gel formulations
por: Obiedallah, Manar M., et al.
Publicado: (2018)

Ammonio Methacrylate Copolymer (Type B)-Diltiazem Interactions in Solid Dispersions and Microsponge Drug-Delivery Systems
por: Kolev, Iliyan, et al.
Publicado: (2022)

Dendrimer entrapped microsponge gel of dithranol for effective topical treatment
por: Tripathi, Pushpendra Kumar, et al.
Publicado: (2019)

Optimization of entrapment efficiency and release of clindamycin in microsponge based gel
por: KHATTAB, ALAA, et al.
Publicado: (2021)

Impact of porous microsponges in minimizing myotoxic side effects of simvastatin
por: Ali, Ahmed U., et al.
Publicado: (2023)

Development of apigenin loaded gastroretentive microsponge for the targeting of Helicobacter pylori
por: Jafar, Mohammed, et al.
Publicado: (2023)

Evaluation of Paeonol Skin-Target Delivery from Its Microsponge Formulation: In Vitro Skin Permeation and In Vivo Microdialysis
por: Li, Sha-Sha, et al.
Publicado: (2013)

Non-Viral Delivery and Therapeutic Application of Small Interfering RNAs
por: Nikitenko, N. A., et al.
Publicado: (2013)

Small circular interfering RNAs (sciRNAs) as a potent therapeutic platform for gene-silencing
por: Jahns, Hartmut, et al.
Publicado: (2021)

Screening of Adapalene Microsponges Fabrication Parameters with Insight on the In vitro Biological Effectiveness
por: Yehia, Rania M, et al.
Publicado: (2022)

A RNA nanotechnology platform for a simultaneous two-in-one siRNA delivery and its application in synergistic RNAi therapy
por: Jang, Mihue, et al.
Publicado: (2016)

Design of Small Interfering RNAs for Antiviral Applications
por: Rothe, Diana, et al.
Publicado: (2010)

Application of quasi-emulsification and modified double emulsification techniques for formulation of tacrolimus microsponges
por: Zaman, Muhammad, et al.
Publicado: (2018)

Formulation and characterization of lornoxicam-loaded cellulosic-microsponge gel for possible applications in arthritis
por: He, Yeteng, et al.
Publicado: (2020)

Bacterial Delivery of RNAi Effectors: Transkingdom RNAi
por: Lage, Hermann, et al.
Publicado: (2010)

Small interfering RNAs on top
Publicado: (2004)

Bioactive Nanocomposite Microsponges for Effective Reconstruction of Critical-Sized Calvarial Defects in Rat Model
por: Wang, Mohan, et al.
Publicado: (2022)

Inhibition of Junín virus replication by small interfering RNAs
por: Artuso, María C., et al.
Publicado: (2009)

Nanoparticle Delivery Platforms for RNAi Therapeutics Targeting COVID-19 Disease in the Respiratory Tract
por: Zhang, Yuan, et al.
Publicado: (2022)

RNAi Therapeutic Platforms for Lung Diseases
por: Fujita, Yu, et al.
Publicado: (2013)

MicroRNAs that interfere with RNAi
por: Massirer, Katlin B., et al.
Publicado: (2013)

Cell type-specific delivery of short interfering RNAs by dye-functionalised theranostic nanoparticles
por: Press, Adrian T., et al.
Publicado: (2014)

RNAi induced in mammalian and Drosophila cells via transfection of dimers and trimers of small interfering RNA
por: Ui-Tei, Kumiko, et al.
Publicado: (2005)

Recombination and Coronavirus Defective Interfering RNAs()
por: Brian, David A., et al.
Publicado: (1997)

Ru@Carbon Nanotube Composite Microsponge: Fabrication in Supercritical CO(2) for Hydrogenation of p-Chloronitrobenzene
por: Ge, Xianghong, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_s95h4ovv9f8f2t835t6ulu8toa