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Thioredoxin 1 protects astrocytes from oxidative stress by maintaining peroxiredoxin activity

Previous studies have demonstrated that thioredoxin 1 (Trx1) exerts neuroprotective effects against cerebral ischemia/reperfusion injury caused by oxidative stress. While Trx1 is known to maintain the anti-oxidant activity of 2-Cys peroxiredoxins (Prdxs), the underlying mechanisms of its protective...

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Detalles Bibliográficos
Autores principales: WANG, MENGFEI, ZHU, KUNTING, ZHANG, LUYU, LI, LINGYU, ZHAO, JING
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768962/
https://www.ncbi.nlm.nih.gov/pubmed/26846911
http://dx.doi.org/10.3892/mmr.2016.4855

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