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Knockout of phospholipase Cε attenuates N-butyl-N-(4-hydroxybutyl) nitrosamine-induced bladder tumorigenesis

Bladder cancer frequently shows mutational activation of the oncogene Ras, which is associated with bladder carcinogenesis. However, the signaling pathway downstream of Ras remains to be fully elucidated. N-butyl-N-(4-hydroxybutyl) nitrosamine (BBN) is able to induce bladder cancer by driving the cl...

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Detalles Bibliográficos
Autores principales:	JIANG, TAIMAO, LIU, TAO, LI, LIN, YANG, ZHIJUN, BAI, YUNFENG, LIU, DONGYE, KONG, CHUIZE
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768990/ https://www.ncbi.nlm.nih.gov/pubmed/26782701 http://dx.doi.org/10.3892/mmr.2016.4762

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