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CDDO-Me Redirects Activation of Breast Tumor Associated Macrophages
Tumor-associated macrophages can account for up to 50% of the tumor mass in breast cancer patients and high TAM density is associated with poor clinical prognosis. Because TAMs enhance tumor growth, development, and metastatic potential, redirection of TAM activation may have significant therapeutic...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769014/ https://www.ncbi.nlm.nih.gov/pubmed/26918785 http://dx.doi.org/10.1371/journal.pone.0149600 |