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CDDO-Me Redirects Activation of Breast Tumor Associated Macrophages

Tumor-associated macrophages can account for up to 50% of the tumor mass in breast cancer patients and high TAM density is associated with poor clinical prognosis. Because TAMs enhance tumor growth, development, and metastatic potential, redirection of TAM activation may have significant therapeutic...

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Detalles Bibliográficos
Autores principales: Ball, Michael S., Shipman, Emilie P., Kim, Hyunjung, Liby, Karen T., Pioli, Patricia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769014/
https://www.ncbi.nlm.nih.gov/pubmed/26918785
http://dx.doi.org/10.1371/journal.pone.0149600