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CD73 Expressed on γδ T Cells Shapes Their Regulatory Effect in Experimental Autoimmune Uveitis
γδ T cells can either enhance or inhibit an adaptive immune response, but the mechanisms involved are not fully understood. Given that CD73 is the main enzyme responsible for conversion of AMP into the immunosuppressive molecule adenosine, we investigated its role in the regulatory function of γδ T...
Autores principales: | Liang, Dongchun, Zuo, Aijun, Zhao, Ronglan, Shao, Hui, Born, Willi K., O'Brien, Rebecca L., Kaplan, Henry J., Sun, Deming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769068/ https://www.ncbi.nlm.nih.gov/pubmed/26919582 http://dx.doi.org/10.1371/journal.pone.0150078 |
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