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ESI-IMS–MS: A method for rapid analysis of protein aggregation and its inhibition by small molecules
Electrospray ionisation-ion mobility spectrometry–mass spectrometry (ESI-IMS–MS) is a powerful method for the study of conformational changes in protein complexes, including oligomeric species populated during protein self-aggregation into amyloid fibrils. Information on the mass, stability, cross-s...
Autores principales: | Young, Lydia M., Saunders, Janet C., Mahood, Rachel A., Revill, Charlotte H., Foster, Richard J., Ashcroft, Alison E., Radford, Sheena E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769093/ https://www.ncbi.nlm.nih.gov/pubmed/26007606 http://dx.doi.org/10.1016/j.ymeth.2015.05.017 |
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