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Hexarelin Protects Rodent Pancreatic Β-Cells Function from Cytotoxic Effects of Streptozotocin Involving Mitochondrial Signalling Pathways In Vivo and In Vitro

Mitochondrial functions are crucial for pancreatic β-cell survival and glucose-induced insulin secretion. Hexarelin (Hex) is a synthetic small peptide ghrelin analogue, which has been shown to protect cardiomyocytes from the ischemia-reperfusion process. In this study, we used in vitro and in vivo m...

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Detalles Bibliográficos
Autores principales: Zhao, Yan, Zhang, Xinli, Chen, Jiezhong, Lin, Chao, Shao, Renfu, Yan, Chunxia, Chen, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769129/
https://www.ncbi.nlm.nih.gov/pubmed/26918825
http://dx.doi.org/10.1371/journal.pone.0149730

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