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Hexarelin Protects Rodent Pancreatic Β-Cells Function from Cytotoxic Effects of Streptozotocin Involving Mitochondrial Signalling Pathways In Vivo and In Vitro
Mitochondrial functions are crucial for pancreatic β-cell survival and glucose-induced insulin secretion. Hexarelin (Hex) is a synthetic small peptide ghrelin analogue, which has been shown to protect cardiomyocytes from the ischemia-reperfusion process. In this study, we used in vitro and in vivo m...
Autores principales: | Zhao, Yan, Zhang, Xinli, Chen, Jiezhong, Lin, Chao, Shao, Renfu, Yan, Chunxia, Chen, Chen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769129/ https://www.ncbi.nlm.nih.gov/pubmed/26918825 http://dx.doi.org/10.1371/journal.pone.0149730 |
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