Optimised Pre-Analytical Methods Improve KRAS Mutation Detection in Circulating Tumour DNA (ctDNA) from Patients with Non-Small Cell Lung Cancer (NSCLC)

INTRODUCTION: Non-invasive mutation testing using circulating tumour DNA (ctDNA) is an attractive premise. This could enable patients without available tumour sample to access more treatment options. MATERIALS & METHODS: Peripheral blood and matched tumours were analysed from 45 NSCLC patients....

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Detalles Bibliográficos
Autores principales: Sherwood, James L., Corcoran, Claire, Brown, Helen, Sharpe, Alan D., Musilova, Milena, Kohlmann, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769175/
https://www.ncbi.nlm.nih.gov/pubmed/26918901
http://dx.doi.org/10.1371/journal.pone.0150197

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