Imputing Variants in HLA-DR Beta Genes Reveals That HLA-DRB1 Is Solely Associated with Rheumatoid Arthritis and Systemic Lupus Erythematosus

The genetic association of HLA-DRB1 with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) is well documented, but association with other HLA-DR beta genes (HLA-DRB3, HLA-DRB4 and HLA-DRB5) has not been thoroughly studied, despite their similar functions and chromosomal positions. We...

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Detalles Bibliográficos
Autores principales: Kim, Kwangwoo, Bang, So-Young, Yoo, Dae Hyun, Cho, Soo-Kyung, Choi, Chan-Bum, Sung, Yoon-Kyoung, Kim, Tae-Hwan, Jun, Jae-Bum, Kang, Young Mo, Suh, Chang-Hee, Shim, Seung-Cheol, Lee, Shin-Seok, Lee, Jisoo, Chung, Won Tae, Kim, Seong-Kyu, Choe, Jung-Yoon, Nath, Swapan K., Lee, Hye-Soon, Bae, Sang-Cheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769216/
https://www.ncbi.nlm.nih.gov/pubmed/26919467
http://dx.doi.org/10.1371/journal.pone.0150283

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