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Therapeutic Effects of Procainamide on Endotoxin-Induced Rhabdomyolysis in Rats
Overt systemic inflammatory response is a predisposing mechanism for infection-induced skeletal muscle damage and rhabdomyolysis. Aberrant DNA methylation plays a crucial role in the pathophysiology of excessive inflammatory response. The antiarrhythmic drug procainamide is a non-nucleoside inhibito...
Autores principales: | Shih, Chih-Chin, Hii, Hiong-Ping, Tsao, Cheng-Ming, Chen, Shiu-Jen, Ka, Shuk-Man, Liao, Mei-Hui, Wu, Chin-Chen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769298/ https://www.ncbi.nlm.nih.gov/pubmed/26918767 http://dx.doi.org/10.1371/journal.pone.0150319 |
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