Releasing Activity Disengages Cohesin’s Smc3/Scc1 Interface in a Process Blocked by Acetylation

Sister chromatid cohesion conferred by entrapment of sister DNAs within a tripartite ring formed between cohesin’s Scc1, Smc1, and Smc3 subunits is created during S and destroyed at anaphase through Scc1 cleavage by separase. Cohesin’s association with chromosomes is controlled by opposing activitie...

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Detalles Bibliográficos
Autores principales: Beckouët, Frederic, Srinivasan, Madhusudhan, Roig, Maurici Brunet, Chan, Kok-Lung, Scheinost, Johanna C., Batty, Paul, Hu, Bin, Petela, Naomi, Gligoris, Thomas, Smith, Alexandra C., Strmecki, Lana, Rowland, Benjamin D., Nasmyth, Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769318/
https://www.ncbi.nlm.nih.gov/pubmed/26895425
http://dx.doi.org/10.1016/j.molcel.2016.01.026

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