Cohesin Releases DNA through Asymmetric ATPase-Driven Ring Opening

Cohesin stably holds together the sister chromatids from S phase until mitosis. To do so, cohesin must be protected against its cellular antagonist Wapl. Eco1 acetylates cohesin’s Smc3 subunit, which locks together the sister DNAs. We used yeast genetics to dissect how Wapl drives cohesin from chrom...

Descripción completa

Detalles Bibliográficos
Autores principales: Elbatsh, Ahmed M.O., Haarhuis, Judith H.I., Petela, Naomi, Chapard, Christophe, Fish, Alexander, Celie, Patrick H., Stadnik, Magda, Ristic, Dejan, Wyman, Claire, Medema, René H., Nasmyth, Kim, Rowland, Benjamin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769319/
https://www.ncbi.nlm.nih.gov/pubmed/26895426
http://dx.doi.org/10.1016/j.molcel.2016.01.025

Ejemplares similares

Ejemplares similares